Charlie has played Marcus for four years over two stints, but announced in November 2013 that he would be quitting to spend more time with his family.
Charlie tweeted a photo of Coronation Street pub The Rovers Return's sign, captioned "Over and out".
He lives in London with his partner Cameron Laux and their children Hal and Georgia, but recently told the Daily Mirror his commute to Manchester was becoming too much.
He said: "It was just getting too difficult. Georgia is at an age now where she was saying, 'How long are you away for this week?' and 'When are you going to be back, Daddy?'
"At my busiest I was getting home late on a Friday night and going back to Manchester on Sunday afternoon. I just wasn't getting that time with my kids."
I'll miss Marcus, he was one of the quiet men of soap. But I never did like him and Todd together.
I also liked Charlie Condou. He was one of the Coronation Street actors on twitter who interacted positively with his fans. Nice!
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