The actor, who plays Sean Tully on Coronation Street, will appear with his mum actress Enid Dunn on the live special edition of the quiz show on Sunday.
Antony will be competing for charity when he and his mum face question master Chris Tarrant.
Antony said: " I am excited and terrified in equal measure."
The show will be screened at 8.30pm tonight, Sunday 18 March on ITV1.
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