On the origin of Mongoloid component in the mitochondrial gene pool of Slavs

In this post are showing some recent genetic (DNA) researches done in different Slavic populations by different Slavic geneticists, to find the true ancestry of Slavic people! So before than some mongol serb call Albanians WRONGLY “not native” iis better for them to do their DNA EXAMINATION, to face the truth of facts and to be proud for their Mongol Ancestry as is nothing wrong in that! On the origin of Mongoloid component in the mitochondrial gene pool of Slavs Journal Russian Journal of Genetics Publisher: MAIK Nauka/Interperiodica distributed exclusively by Springer Science+Business Media LLC. ISSN: 1022-7954 (Print) 1608-3369 (Online) Issue: Volume 44, Number 3 / March, 2008 Category: Human Genetics DOI: 10.1007/s11177-008-3016-9 Pages: 344-349 Subject Collection: Biomedical and Life Sciences SpringerLink Date: Friday, April 04, 2008 http://www.springerlink.com/content/nt3lj1301228358r/ Genetists: B. A. Malyarchuk1 , M. A. Perkova1 and M. V. Derenko1 (1) Institute of Biological Problems of the North, Russian Academy of Sciences, Magadan, 685000, Russia Received: 21 December 2006 Published online: 4 April 2008 Abstract: The data on mitochondrial DNA (mtDNA) restriction polymorphism in Czech population (n = 279) are presented. It was demonstrated that in terms of their structure, mitochondrial gene pools of Czechs and other Slavic populations (Russians, Poles, Slovenians, and Bosnians) were practically indistinguishable. In Czechs, the frequency of eastern-Eurasian (Mongoloid) mtDNA lineages constituted 1.8%. The spread of eastern-Eurasian mtDNA lineages belonging to different ethnolinguistic groups in the populations of Europe was examined. Frequency variations of these DNA lineages in different Slavic groups was observed, with the range from 1.2 and 1.6% in Southern and Western Slavs (Serbs), respectively, to 1.3 to 5.2% in Eastern Slavs, the Russian population of Eastern Europe. The highest frequency of Mongoloid component was detected in the mitochondrial gene pools of Russian populations from the Russian North and the Northwestern region of Russia. This finding can be explained in terms of assimilation of northern-European Finno-Ugric populations during the formation of the Russian population of these regions. The origin of Mongoloid component in the gene pools of different groups of Slavs is discussed. Original Russian Text © B.A. Malyarchuk, M.A. Perkova, M.V. Derenko, 2008, published in Genetika, 2008, Vol. 44, No. 3, pp. 401–406. It is suggested that after the decay of Avar Khaganate the populations included into it were assimilated by Slavic tribes [34]. It is thereby suggested that rather high frequencies of eastern-Eurasian mtDNA lineages observed in the gene pools of some populations of Western and Southern Slavs (Serbs) (especially on the territoryof former Avar Khaganate) can be considered as a consequence of the process described. Reconstructing the phylogeny of African mitochondrial DNA lineages in Slavs Geneticists: Boris A Malyarchuk, Miroslava Derenko, Maria Perkova, Tomasz Grzybowski, Tomas Vanecek and Jan Lazur This study said that the "Mongoloid component in the mitochondrial gene pool of Slavs" constitutes only 1.2-1.6% of southern and western Slavs. That is hardly "high frequencies". http://www.nature.com/ejhg/journal/vaop/ncurrent/abs/ejhg200870a.html 1. Genetics Laboratory, Institute of Biological Problems of the North, Far-East Branch of Russian Academy of Sciences, Magadan, Russia 2. Forensic Medicine Institute, Ludwik Rydygier Medical College, Nicolaus Copernicus University, Bydgoszcz, Poland 3. Department of Pathology, Medical Faculty Hospital, Charles University, Pilsen, Czech Republic 4. Department of Laboratory Medicine, LABMED, Kosice, Slovakia Correspondence: Dr BA Malyarchuk, Genetics Laboratory, Institute of Biological Problems of the North, Far-East Branch of Russian Academy of Sciences, Portovaya street, 18, Magadan 685000, Russia. Tel: +7 4132 631164; Fax: +7 4132 634463; E-mail: malyarchuk@ibpn.ru Received 27 November 2007; Revised 7 February 2008; Accepted 28 February 2008; Published online 9 April 2008. Abstract: To elucidate the origin of African-specific mtDNA lineages, revealed previously in Slavonic populations (at frequency of about 0.4%), we completely sequenced eight African genomes belonging to haplogroups L1b, L2a, L3b, L3d and M1 gathered from Russians, Czechs, Slovaks and Poles. Results of phylogeographic analysis suggest that at least part of the African mtDNA lineages found in Slavs (such as L1b, L3b1, L3d) appears to be of West African origin, testifying to an opportunity of their occurrence as a result of migrations to Eastern Europe through Iberia. However, a prehistoric introgression of African mtDNA lineages into Eastern Europe (approximately 10 000 years ago) seems to be probable only for European-specific subclade L2a1a, defined by coding region mutations at positions 6722 and 12903 and detected in Czechs and Slovaks. Further studies of the nature of African admixture in gene pools of Europeans require the essential enlargement of databases of African complete mitochondrial genomes. Link: http://www.nature.com/ejhg/journal/vaop/ncurrent/fig_tab/ejhg200870ft.html Figure 1: Complete genome-based phylogenetic tree of African-specific haplogroups found in Slavonic gene pools. The tree is rooted in macrohaplogroup L. Numbers along links refer to substitutions scored relative to the rCRS.20 Transversions are further specified, recurrent mutations are underlined, 'd' denotes a deletion. Two additional complete sequences were taken from the literature29, 30 and designated by AO and AT, respectively, followed by '_' and the original sample code. Table 1. mtDNA control region sequences belonging to African-specific haplogroups detected in Slavs Abbreviation: HG, haplogroup; HVS, hypervariable segment. Nucleotide positions numbers refer to transitions scored relative to the revised Cambridge reference sequence (rCRS).20 Transversions are further specified, 'i' denotes an insertion of nucleotide. Unique mutations are shown in bold.